3. Doctor Destiny
Doctor Destiny is one of the worst villains ever by DC Universe. He was blessed with an ability to control dreams, which he used to replace superheroes with a belief that he would not be caught ever. His appearance in The Sandman by Neil Gaiman brings him back with his powers, but Justice League restricts his powers to control dreams.
4. Black Hand
Black Hand first appeared in Green Lantern (vol. 2) #29 in 1964. As the name suggests, he had his powers and hands had nothing to do with each other. He was a crazy scientist who wanted to steal the powers of Green Lantern, but he was knocked by down by Hal. Later he turned into a serial killer and used to sleep in an open grave.