He’s Clueless about Drugs
Although Captain America has got enhanced powers from the super serum, he is a bit gullible when it comes to recreational drugs. In one storyline for the comics, The Captain gets exposed to a drug called “Ice.” He becomes overly aggressive and spirals into an episode of insanity. The Avengers save him by performing a drug transfusion that also took away his powers. When he was offered the serum again, he declined…but not for long because it is the comics.