Wolverinepool
All it takes is the Weapon X program which can turn you into anything like it did to Merc. His skeleton was bonded with Adamantium and the outcome was crazy. Created by Fabian Nicieza, and Reilly Brown, Wolverinepool first appeared in Cable & Deadpool #46 in 2007. So what would he use the most, swords or claws?
Lady Deadpool
All the way from the alternate reality Earth-3010 and created by Victor Gischler and Rob Liefeld, Lady Deadpool first appeared in Deadpool: Merc with a Mouth #7. This lady version of Deadman is also dubbed as Wanda Wilson. She is one of the rebels who fight with loyalists in the United States.